Hepatotoxicity severe and sometimes fatal hepatotoxicity has occurred in clinical trials see warnings and precautions 5. Tarceva is not recommended for use in combination with platinumbased chemotherapy see clinical studies 14. Tell your healthcare provider about all the medicines you take, including prescription and overthecounter medicines, vitamins, and herbal supplements. Indications the indications below including fdaapproved indications and compendial uses are considered covered benefits provided that all the approval criteria are met and the member has no exclusions to the prescribed therapy. Sunitinib therapy for metastatic renal cell carcinoma. Opdivo nivolumab is indicated for the treatment of patients with recurrent or metastatic squamous cell carcinoma of the head and neck scchn with disease progression on or after platinumbased therapy. Highlights of prescribing information these highlights do not include all the information needed to use jevtana safely and effectively. Elevated lipase was observed in 40% of patients treated with nexavar compared to 37% of patients in the placebotreated group. Highlights of prescribing information these highlights. According to the drug monograph, a standard dose modification in 12. This document contains confidential and proprietary information of cvscaremark and cannot be. Highlights of prescribing information these highlights do. Highlights of prescribing information these highlights do not include all the information needed to use sutent safely and effectively. Pfizer reserves the right to rescind, revoke or amend this offer without.
The enbreletanercept instructions for use insert for each presentation contains more detailed instructions on injection site selection and the preparation of enbrel. When possible, interrupt therapy with brilinta for fivedays prior to surgery that has a major risk of bleeding. Medicines are sometimes prescribed for purposes other than those listed in a medication guide. Highlights of prescribing information these highlights do not include all the information needed to use votrient safely and effectively. Highlights of prescribing information recurrent or.
General information about the safe and effective use of sutent. If a dose is missed, take the next dose at the regular time. This letter is to inform you of an important update to the sutent prescribing information pi. As a firsttime treatment given with chemotherapy called folfox. To continue on sutent, a healthcare provider must write a separate prescription to be filled at a participating specialty pharmacy.
Prescribing information update for sutent sunitinib. As a condition precedent of the copayment support provided under this program, e. Sutent is a prescription medicine used to treat people with. Get emergency help right away if you get symptoms such as chest pain, shortness of breath, racing heartbeat, swelling in lower legs, feet and abdomen, feel lightheaded or faint, tiredness, nausea, vomiting, or sweat a lot. Hepatotoxicity see full prescribing information for complete boxed warning. If dose is increased, the patient should be monitored carefully for toxicity see drug interactions 7. Read all of this leaflet carefully before you start taking this medicine because it contains important information for you. Highlights of prescribing information patients at risk. See full prescribing information for complete boxed. Medicaid, tricare, veterans affairs health care, a state prescription drug assistance program, or the government health insurance plan available in puerto. Patients receiving therapy with sunitinib should be monitored by a qualified. Each capsule contains sunitinib malate, equivalent to 37. If dose is increased, the patient should be monitored carefully for toxicitysee drug interactions 7.
The recommended dose of sutent for gastrointestinal stromal tumor gist and advanced renal cell carcinoma rcc is one. Do not take 2 doses at the same time to make up for a missed dose. Sunitinib therapy for metastatic renal cell carcinoma ncbi. Inlyta may cause fertility problems in males and females, which may affect your ability to have a child. Monitor hepatic function prior to and during treatment see warnings and precautions 5. This trial voucher is valid once per patient for a 1month 28day trial of 12. Keep sutent and all medicines out of the reach of children.
Ctcae grade 3 or 4 lipase elevations occurred in 9% of patients in each group. Interrupt and then reduce or discontinue stivarga for hepatotoxicity as manifested by elevated liver. Sutent is used to treat advanced kidney cancer advanced renal cell carcinoma or rcc. Sutent is a medication used to treat adult patients with kidney cancer that has been surgically removed and at high risk of recurrence, or advanced kidney cancer that has spread to other organs. Sutent is used to treat adults with kidney cancer that has not spread localized and who are at high risk of rcc coming back again after having kidney surgery. Highlights of prescribing information these highlights do not include all the information needed to use. Talk to your healthcare provider if this is a concern for you. This leaflet is part iii of a threepart product monograph published when sutent was.
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